Observation techniques and experimental design

hydrochlorothiazide detection in urine samples by hplc-dad and experimental design dispersive l-l microextraction

hydrochlorothiazide (hct) is a diuretic agent which is shown to be effective in the treatment of hypertension. literature reports have demonstrated that urinary excretion data may be used to assess the bioavailability of various formulations containing this thiazide. also hct consumption by the athletes is one of the drugs which should be regulated by world anti-doping agency (wada), because of...

High-Contrast Algorithm Behavior: Observation, Conjecture, and Experimental Design

After extensive experiments with two algorithms, CPLEX and our implementation of all-integer dual simplex, we observed extreme differences between the two on a set of design automation benchmarks. In many cases one of the two would find an optimal solution within seconds while the other timed out at one hour. We conjecture that this contrast is accounted for by the extent to which the constrain...

Teaching Experimental Design Techniques to Industrial Engineers*

Experimental Design (ED) is a powerful technique for understanding a process, studying the impact of potential variables or factors affecting the process and thereby providing spontaneous insight for continuous quality improvement possibilities. ED has proved to be very effective for improving the process yield, process capability, process performance and reducing process variability. However r...

The specification of rank reducing observation sets in experimental design

If observations are lost from an experiment involving one or more forms of blocking, it can happen that the resultant design is treatment disconnected which has serious implications for the experiment. A method is described in this paper for specifying each set of observations which has the property that a treatment disconnected design will result if this observation set is missing. Some implic...

Basic Biometric Techniques in Experimental Design and Analysis